Morphology: reactive lymphocytes have a heterogenous appearance with variable size, nuclear shape, and amount and color of cytoplasm. Compared to non-reactive lymphocytes, reactive lymphocytes are usually larger with darker blue cytoplasm,… Read more Reactive Lymphocytes →
Lymphoid neoplasia is the most common form of hematopoeitic neoplasia in domestic animals. Lymphoid neoplasia can be categorized as lymphosarcomas (neoplastic lymphocytes from solid tumors in extramedullary tissue) or leukemias (neoplastic lymphocytes… Read more Lymphocytic Leukemias →
Morphology: lymphocytes with pink or red cytoplasmic granules. Granular lymphocytes are either cytotoxic T-cells or natural killer cells. Look alike: granulocytes (eosinophils, basophils) Clinical relevance: present in low numbers in healthy animals… Read more Granular Lymphocytes →
Also called: mature neutrophils, segmented neutrophils (segs), polymorphonuclear cells (PMN) Morphology: granulocyte with an indented (segmented) nucleus and white or pale pink cytoplasm. Canine and bovine neutrophils may contain small pink… Read more Neutrophils →
Morphology: poikilocyte is a generic term to describe red blood cells with abnormal shape. Poikilocytosis refers to large numbers of abnormally shaped red blood cells. Commonly seen with: poikilocytosis may include… Read more Poikilocytosis →
Morphology: leukocytes with pleomorphic nuclei (usually lobulated but may be round or kidney-shaped) and blue-gray cytoplasm containing occasional vacuoles or fine pink granules. Monocytes are larger than most other leukocytes.… Read more Monocytes →
Morphology: long worm-like organism in the background of peripheral blood smear. Look alike: trypanosomes, other filarial organisms such as equine onchocerciasis (Onchocerca cervicalis) and canine heartworm (Dirofilaria immitis) Clinical relevance: Setaria equina is… Read more Setaria equina →
Morphology: small round leukocytes with round or indented nuclei, dark clumped chromatin, and small amounts of light blue cytoplasm. Cattle have small lymphocytes (as described), as well as large lymphocytes with… Read more Mature Lymphocytes →
Cells and Smears 