Ghost Cells

Ghost Cells 1 (Equine 1 - IMHA) ARROWS
Ghost cells (arrows). Polychromatophils, macrocytes, microcytes, and platelets also visible (not marked). Equine (IMHA).

Morphology: red blood cells that stain very pale due to loss of hemoglobin through intravascular lysis.

Commonly seen with: other features of immune-mediated hemolytic anemia (IMHA) including spherocytes, polychromatophils, and agglutination of red blood cells.

Clinical relevance: indicates intravascular hemolysis. Most commonly observed with IMHA, but may also be associated with intravascular hemolysis caused by other conditions (oxidant injury, parasitemia, snake envenomation, hypophosphatemia).

Ghost Cells 2 (Feline 1 - IMHA) ARROWS
Ghost cells (arrows). Polychromatophils, spherocytes, and platelets also visible (not marked). Feline (IMHA).

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