Reticulocytes
Morphology: immature red blood cells that stain blue with new-methylene blue due to precipitation of retained cytoplasmic RNA. Aggregate reticulocytes are less mature with large amounts of RNA that form dark… Read more Reticulocytes →
Polychromatophils
Morphology: immature red blood cells that stain dark purple on Romanowsky stains (Wright’s, Diff-Quick) due to retained cytoplasmic RNA. Larger than normal red cells. Commonly seen with: features of regenerative anemia (macrocytosis,… Read more Polychromatophils →
Eccentrocytes
Morphology: red blood cells with a clear crescent-shaped area along one side of the periphery. Formed by the fusion of two layers of oxidized cell membrane with no hemoglobin in between.… Read more Eccentrocytes →
Cells and Smears 