Codocytes

Also called: target cells
Morphology: canine red blood cells with a bullseye appearance. Caused by increased ratio of cell membrane to hemoglobin content which results in a central bulge.
Look alike: torocytes
Clinical relevance: may be associated with regenerative anemia (polychromatophilic codocytes), iron deficiency anemia (hypochromic codocytes), liver disease and hypercholesterolemia (normochromic codocytes). Only observed in canine red blood cells with central pallor.

